原口 徳子

発表論文(平成28年度~平成29年度)

1.Yang HJ, Iwamoto M, Hiraoka Y, Haraguchi T.
Function of nuclear membrane proteins in shaping the nuclear envelope integrity during closed mitosis.
J Biochem. ,2017 Apr 8.
Pubmed ID: 28398483
[領域内共同研究:平岡、原口] 
2.Iwamoto M, Osakada H, Mori C, Fukuda Y, Nagao K, Obuse C, Hiraoka Y, Haraguchi T.
Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in ciliate Tetrahymena.
J. Cell Sci.,2017
Pubmed ID: 28386019
[領域内共同研究:小布施・平岡・原口]
3.Kaur H, Sparvoli D, Osakada H, Iwamoto M, Haraguchi T, Turkewitz AP.
A late endosomal syntaxin and the AP-3 complex are required for formation and maturation of lysosome-related secretory organelles (mucocysts) in Tetrahymena thermophila .
Mol. Biol. Cell.,2017 April 5.
Pubmed ID: 28381425
[国際活動支援班の成果]
4.Chikashige Y, Yamane M, Okamasa K, Osakada H, Tsutsumi C, Nagahama Y, Fukuta N, Haraguchi T, Hiraoka Y.
Fission yeast APC/C activators Slp1 and Fzr1 sequentially trigger two consecutive nuclear divisions during meiosis.
FEBS Lett.,2017 Feb 28.
Pubmed ID: 28245054
[領域内共同研究:原口・平岡]
5. Yang HJ, Osakada H, Kojidani T, Haraguchi T, Hiraoka Y.
Lipid droplet dynamics during Schizosaccharomyces pombe sporulation and their role in spore survival.
Biol Open.,2017 Jan 3. pii: bio.022384.
Pubmed ID: 28011631
[領域内共同研究:原口・平岡]
6. Koyama M, Nagakura W, Tanaka H, Kujirai T, Chikashige Y, Haraguchi T, Hiraoka Y, Kurumizaka H.
In vitro reconstitution and biochemical analyses of the Schizosaccharomyces pombe nucleosome.
Biochem Biophys Res Commun. , 2016
Pubmed ID: 27890612  
 [領域内共同研究:原口・平岡・胡桃坂]
7. Matsuda A, Asakawa H, Haraguchi T, Hiraoka Y.
Spatial organization of the Schizosaccharomyces pombe genome within the nucleus.
Yeast.,2016 Oct 21.
Pubmed ID: 27766670 
 [領域内共同研究:淺川・原口・平岡]
8. Sato Y, Kujirai T, Arai R, Asakawa H, Ohtsuki C, Horikoshi N, Yamagata K, Ueda J, Nagase T, Haraguchi T, Hiraoka Y, Kimura A, Kurumizaka H, Kimura H.
A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation.
J Mol Biol. ,Oct 9;428(20):3885-3902.
Pubmed ID: 27534817  
 [領域内共同研究:木村・浅川・原口・山縣・上田・平岡・胡桃坂]
9. Kobayashi S, Iwamoto M, Haraguchi T.
Live correlative light-electron microscopy to observe molecular dynamics in high resolution.
Microscopy (Oxf). ,2016 Aug;65(4):296-308.
Pubmed ID: 27385786 責任著者
10. Gómez-Saldivar G, Fernandez A, Hirano Y, Mauro M, Lai A, Ayuso C, Haraguchi T, Hiraoka Y, Piano F, Askjaer P.
Identification of Conserved MEL-28/ELYS Domains with Essential Roles in Nuclear Assembly and Chromosome Segregation
PLoS Genet, 2016
Pubmed ID: 27341616
[領域内共同研究:原口・平岡]
11. Tange Y, Chikashige Y, Takahata S, Kawakami K, Higashi M, Mori C, Kojidani T, Hirano Y, Asakawa H, Murakami Y, Haraguchi T, Hiraoka Y.
Inner nuclear membrane protein Lem2 augments heterochromatin formation in response to nutritional conditions.
Genes Cells,2016 Aug;21(8):812-32.
Pubmed ID: 27334362
[領域内共同研究:淺川・原口・平岡]
12. Tsuchiya M, Ogawa H, Koujin T, Kobayashi S, Mori C, Hiraoka Y, Haraguchi T.
Depletion of autophagy receptor p62/SQSTM1 enhances the efficiency of gene delivery in mammalian cells.
FEBS Lett,2016 Aug;590(16):2671-80.
Pubmed ID: 27317902 責任著者
[領域内共同研究:平岡・原口]
13. Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, Toyoshima F.
Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1.
Nat Commun, 2016
Pubmed ID: 27292265

発表論文(平成25年度~平成27年度)

1. Iwamoto, M., Hiraoka, Y., Haraguchi, T.
Uniquely designed nuclear structures of lower eukaryotes
Current Opinion in Cell Biology, 2016
(web: http://www.sciencedirect.com/science/article/pii/S0955067416300266#)
責任著者 [領域内共同研究:平岡・原口]
2. Ding, D. Q., Haraguchi, T., and Hiraoka, Y.
A cohesin-based structural platform supporting homologous chromosome pairing in meiosis
Curr Genet, 2016
Pubmed ID: 26856595
[領域内共同研究:原口・平岡]
3. Asakawa, H., Yang, H.-J., Hiraoka, Y., and Haraguchi, T.
Virtual nuclear envelope breakdown and its regulators in fission yeast meiosis
Front. Cell Dev. Biol, 2016
Pubmed ID: 26870731
責任著者 [領域内共同研究:淺川・平岡・原口]
4. Yang, H. J., Haraguchi, T., and Hiraoka, Y.
A nucleoporin that facilitates meiotic kinetochore reorganization
Cell Cycle, 2016
Pubmed ID: 26727711
[領域内共同研究:原口・平岡]
5. Ohtsuki, T., Miki, S., Kobayashi, S., Haraguchi, T., Nakata, E., Hirakawa, K., Sumita, K., Watanabe, K., and Okazaki, S.
The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates
Sci Rep, 2015
Pubmed ID: 26686907
6. Yamamoto, J., Oura, M., Yamashita, T., Miki, S., Jin, T., Haraguchi, T., Hiraoka, Y., Terai, H., and Kinjo, M.
Rotational diffusion measurements using polarization-dependent fluorescence correlation spectroscopy based on superconducting nanowire single-photon detector
Optics Express,2015
Pubmed ID: 26699052
[領域内共同研究:原口・平岡]
7. Ding, D. Q., Matsuda, A., Okamasa, K., Nagahama, Y., Haraguchi, T., and Hiraoka, Y.
Meiotic cohesin-based chromosome structure is essential for homologous chromosome pairing in Schizosaccharomyces pombe
Chromosoma, 2015
Pubmed ID: 26511279
[領域内共同研究:平岡・原口]
8. Chikashige, Y., Arakawa, S., Leibnitz, K., Tsutsumi, C., Mori, C., Osakada, H., Murata, M., Haraguchi, T., and Hiraoka, Y.
Cellular economy in fission yeast cells continuously cultured with limited nitrogen resources
Sci Rep 5, 15617, 2015
Pubmed ID: 26486373
[領域内共同研究:原口・平岡]
9. Yang, H. J., Asakawa, H., Haraguchi, T., and Hiraoka, Y.
Nup132 modulates meiotic spindle attachment in fission yeast by regulating kinetochore assembly
J Cell Biol, 2015
Pubmed ID: 26483559
[領域内共同研究:淺川・原口・平岡]
10. Tsuchiya, M., Isogai, S., Taniguchi, H., Tochio, H., Shirakawa, M., Morohashi, K., Hiraoka, Y., Haraguchi, T., and Ogawa, H.
Selective autophagic receptor p62 regulates the abundance of transcriptional coregulator ARIP4 during nutrient starvation
Sci Rep 5, 14498, 2015
Pubmed ID:26412716
[領域内共同研究:平岡・原口]
11. Iwamoto, M., Hiraoka, Y., Haraguchi, T.
The nuclear pore complex acts as a master switch for nuclear differentiation
Commun Integr Biol , 2015
Pubmed ID:26479399
責任著者、[領域内共同研究:平岡、原口]
12. Kobayashi, S., Haraguchi, T.
A novel pathway to detect and cope with exogenous dsDNA
Commun Integr Biol, 2015
(web : http://www.tandfonline.com/doi/full/10.1080/19420889.2015.1065361#abstract)
責任著者
13. Ruan, K., Yamamoto, T. G., Asakawa, H., Chikashige, Y., Kimura, H., Masukata, H., Haraguchi, T., and Hiraoka, Y.
Histone H4 acetylation required for chromatin decompaction during DNA replication
Sci Rep , 2015
Pubmed ID: 4520004 [領域内共同研究:淺川・木村・原口・平岡]
14. Matsuda, A., Chikashige, Y., Ding, D. Q., Ohtsuki, C., Mori, C., Asakawa, H., Kimura, H., Haraguchi, T., and Hiraoka, Y.
Highly condensed chromatins are formed adjacent to subtelomeric and decondensed silent chromatin in fission yeast
Nat Commun , 2015
Pubmed ID: 26205977 [領域内共同研究:淺川・木村・原口・平岡]
15. Asakawa, H., Mori, C., Ohtsuki, C., Iwamoto, M. Hiraoka, Y., Haraguchi, T.
Uncleavable Nup98-Nup96 is functional in the fission yeast Schizosaccharomyces pombe
FEBS Open Bio , 2015
Pubmed ID: 26137436 責任著者、[領域内共同研究:淺川・平岡・原口]
16. Kobayashi, S., Koujin, T., Kojidani, T., Osakada, H., Mori, C., Hiraoka, Y., and Haraguchi, T.
BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy
Proc Natl Acad Sci U S A, 2015
Pubmed ID: 25991860 責任著者、[領域内共同研究:原口・平岡]
※毎日新聞、朝日新聞、神戸新聞、web newsなどで取りあげられました。 
17. Iwamoto, M., Koujin, T., Osakada, H., Mori, C., Kojidani, T., Matsuda, A., Asakawa, H., Hiraoka, Y., and Haraguchi, T.
Biased assembly of the nuclear pore complex is required for somatic and germline nuclear differentiation in Tetrahymena
J Cell Sci 128, 1812-1823, 2015
Pubmed ID: 25788697 責任著者、[領域内共同研究:原口・淺川・平岡]
18. Liu, N. A., Sun, J., Kono, K., Horikoshi, Y., Ikura, T., Tong, X., Haraguchi, T., and Tashiro, S.
Regulation of homologous recombinational repair by lamin B1 in radiation-induced DNA damage
FASEB J, 2015
Pubmed ID: 25733566 [領域内共同研究:田代・原口]
19. Haraguchi, T., Osakada, H., and Koujin, T.
Live CLEM imaging to analyze nuclear structures at high resolution
Methods Mol Biol , 2015
Pubmed ID: 25555577 責任著者、筆頭著者
20. Ruan, K., Yamamoto, T. G., Asakawa, H., Chikashige, Y., Masukata, H., Haraguchi, T., and Hiraoka, Y.
Meiotic nuclear movements in fission yeast are regulated by the transcription factor Mei4 downstream of a Cds1-dependent replication checkpoint pathway
Genes Cells , 2015
Pubmed ID: 25492408 [領域内共同研究:平岡・原口・淺川]
21. Yamashita, T., Liu, D., Miki, S., Yamamoto, J., Haraguchi, T., Kinjo, M., Hiraoka, Y., Wang, Z., and Terai, H.
Fluorescence correlation spectroscopy with visible-wavelength superconducting nanowire single-photon detector
Opt Express 22, 28783-28789, 2014
Pubmed ID: 25402117 [領域内共同研究:原口・平岡]
22. Oana, H., Nishikawa, K., Matsuhara, H., Yamamoto, A., Yamamoto, T. G., Haraguchi, T., Hiraoka, Y., and Washizu, M.
Non-destructive handling of individual chromatin fibers isolated from single cells in a microfluidic device utilizing an optically driven microtool
Lab Chip 14, 696-704, 2014
Pubmed ID: 24356711 [領域内共同研究:原口・平岡]
23. Kuramoto, K., Sakai, F., Yoshinori, N., Nakamura, T. Y., Wakabayashi, S., Kojidani, T., Haraguchi, T., Hirose, F., and Osumi, T.
Deficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction
Mol Cell Biol 34, 2721-2731, 2014
Pubmed ID: 24820416
24. Iwamoto, M., Mori, C., Hiraoka, Y., and Haraguchi, T.
Puromycin resistance gene as an effective selection marker for ciliate Tetrahymena
Gene 534, 249-255, 2014
Pubmed ID: 24185080 責任著者、[領域内共同研究:平岡・原口]
25. Chikashige, Y., Yamane, M., Okamasa, K., Mori, C., Fukuta, N., Matsuda, A., Haraguchi, T., and Hiraoka, Y.
Chromosomes rein back the spindle pole body during horsetail movement in fission yeast meiosis
Cell Struct Funct 39, 93-100, 2014
Pubmed ID: 24954111 [領域内共同研究:平岡・原口]
26. Asakawa, H., Yang, H. J., Yamamoto, T. G., Ohtsuki, C., Chikashige, Y., Sakata-Sogawa, K., Tokunaga, M., Iwamoto, M., Hiraoka, Y., and Haraguchi, T.
Characterization of nuclear pore complex components in fission yeast Schizosaccharomyces pombe
Nucleus 5, 149-162, 2014
Pubmed ID: 24637836 責任著者、[領域内共同研究:淺川・平岡・原口]
27. Asakawa, H., Hiraoka, Y., and Haraguchi, T.
A method of correlative light and electron microscopy for yeast cells
Micron 61, 53-61, 2014
Pubmed ID: 24792447 責任著者、[領域内共同研究:淺川・平岡・原口]
28. Iwamoto, M., Asakawa, H., Ohtsuki, C., Osakada, H., Koujin, T., Hiraoka, Y., and Haraguchi, T.
Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans
Monoclon Antib Immunodiagn Immunother 32, 81-90, 2013
Pubmed ID: 23607342 責任著者、[領域内共同研究:平岡・原口]
29. Fujita, N., Morita, E., Itoh, T., Tanaka, A., Nakaoka, M., Osada, Y., Umemoto, T., Saitoh, T., Nakatogawa, H., Kobayashi, S., Haraguchi, T., Guan, J. L., Iwai, K., Tokunaga, F., Saito, K., Ishibashi, K., Akira, S., Fukuda, M., Noda, T., and Yoshimori, T.
Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin
J Cell Biol 203, 115-128, 2013
Pubmed ID: 24100292
30. Ding, D. Q., Haraguchi, T., and Hiraoka, Y.
The role of chromosomal retention of noncoding RNA in meiosis
Chromosome Res 21, 665-672, 2013
Pubmed ID: 24173580 [領域内共同研究:平岡・原口]

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